Clinical References on the ingredients in OmegaMAXX™

Lee SJ, Bai SK, Lee KS, et al.Astaxanthin inhibits nitric oxide production and inflammatory gene expression by suppressing I(kappa)B kinase-dependent NF kappaB activation. Mol Cells. 2003 Aug 31; 16(1):97-105

Reginster JY, Gillot V, Bruyere O, et al. Evidence of nutriceutical effectiveness in the treatment of osteoarthritis. Curr Rheumatol Rep. 2000 Dec;2(6):472-7. Review.

Spiller G. Studies show BioAstin relieves pain and improves performance in patients with rheumatoid arthritis and carpal tunnel syndrome in double blind, placebo controlled studies. Health research studies center in Los Altos, CA.

11: Palozza P, Krinsky NI.
Astaxanthin and canthaxanthin are potent antioxidants in a membrane model.
Arch Biochem Biophys. 1992 Sep;297(2):291-5.
PMID: 1497349 [PubMed - indexed for MEDLINE]

12: Miki W.
Recent advances in carotenoid studies--metabolisms and bioactivities.
J Nutr Sci Vitaminol (Tokyo). 1992;Spec No:469-72. Review. No abstract available.
PMID: 1297791 [PubMed - indexed for MEDLINE]

1: Lockwood SF, Gross GJ.
Disodium disuccinate astaxanthin (Cardax): antioxidant and antiinflammatory cardioprotection.
Cardiovasc Drug Rev. 2005 Fall;23(3):199-216.
PMID: 16252014 [PubMed - in process]

6: Hussein G, Goto H, Oda S, Iguchi T, Sankawa U, Matsumoto K, Watanabe H.
Antihypertensive potential and mechanism of action of astaxanthin: II. Vascular reactivity and hemorheology in spontaneously hypertensive rats.
Biol Pharm Bull. 2005 Jun;28(6):967-71.
PMID: 15930728 [PubMed - in process]

11: Hix LM, Lockwood SF, Bertram JS.
Bioactive carotenoids: potent antioxidants and regulators of gene expression.
Redox Rep. 2004;9(4):181-91. Review.
PMID: 15479561 [PubMed - indexed for MEDLINE]

13: Naito Y, Uchiyama K, Aoi W, Hasegawa G, Nakamura N, Yoshida N, Maoka T,
Takahashi J, Yoshikawa T.
Prevention of diabetic nephropathy by treatment with astaxanthin in diabetic db/db mice.
Biofactors. 2004;20(1):49-59.
PMID: 15096660 [PubMed - indexed for MEDLINE]

16: Chew BP, Park JS.
Carotenoid action on the immune response.
J Nutr. 2004 Jan;134(1):257S-261S. Review.
PMID: 14704330 [PubMed - indexed for MEDLINE]

21: Guerin M, Huntley ME, Olaizola M.
Haematococcus astaxanthin: applications for human health and nutrition.
Trends Biotechnol. 2003 May;21(5):210-6. Review.
PMID: 12727382 [PubMed - indexed for MEDLINE]

31: Jyonouchi H, Sun S, Iijima K, Gross MD.
Antitumor activity of astaxanthin and its mode of action.
Nutr Cancer. 2000;36(1):59-65.
PMID: 10798217 [PubMed - indexed for MEDLINE]

32: Naguib YM.
Antioxidant activities of astaxanthin and related carotenoids.
J Agric Food Chem. 2000 Apr;48(4):1150-4.
PMID: 10775364 [PubMed - indexed for MEDLINE]